Development of adenocarcinoma in chronic fistula in Crohn's disease
| Journal | Volume 68 - 2005 |
| Issue | Fasc.1 - Case reports |
| Author(s) | S. Laurent, A. Barbeaux, B. Detroz, O. Detry, E. Louis, J. Belaiche, M. Meurisse |
| Full article |
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| (1) Dpt of Abdominal Surgery, (3) Dpt of gastroenterology, CHU Sart Tilman B35, B-4000 Liège, Belgium ; (2) Dpt of Medical Oncology, Cliniques Universitaires Mont- Godinne, Rue Docteur G Therasse, B-5530 Mont-Godinne. |
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The authors report the case of a 55 yr-old woman suffering from Crohn's disease since 31 years with stricture and fistulas developed in the ileocolic junction and anorectal portion. Long- standing anorectal fistulas and stricture led to adenocarcinoma and finally fistulisation in the vagina. Diagnosis was made by per- ineal examination with biopsies under general anaesthesia. Treatment was first posterior pelvectomy with resection of the anterior wall of vagina. Secondarily, radiochemotherapy was administrated. The authors discuss the incidence and risk factors of carcinoma in Crohn's disease with chronic fistulas. (Acta gastro- enterol. belg., 2005, 68, 98-100). |
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© Acta Gastro-Enterologica Belgica. |
